American Chesapeake Club

Established 1918

Exercise-Induced Collapse

What is Exercise-Induced Collapse?  Exercise-Induced Collapse is a syndrome in which there is a decrease in the transmission of signals from the brain to the muscles in the rear legs of dogs during intense exercise. This syndrome is quite common in Labrador Retrievers, but also occurs in several other breeds including Chesapeake Bay Retrievers.

 

Is it inherited? Yes

 

How is it inherited? The mode of inheritance for Exercise-Induced Collapse is autosomal recessive. This means that both parents must carry one copy of the causative genes in order for the condition to be passed on to offspring. Dogs with two copies of the gene will be susceptible to collapse under conditions of strenuous exercise.

 

Can it be prevented? Yes. The gene associated with Exercise-Induced collapse was identified by researchers at the University of Minnesota in 2007 and a genetic test was developed following that important research. Breeders are advised to test both dogs and bitches prior to breeding to avoid pairings that will produce affected offspring. The test is available at most laboratories providing canine genetic testing.

Links

Dynamin-1 Associated Exercise-Induced Collapse – University of Minnesota College of Veterinary Medicine

EIC Test Result Interpretation – University of Minnesota Veterinary Diagnostic Laboratory